Given the high incidence of substance abuse in bipolar disorder, the supplement N-acetylcysteine (NAC) should be considered for use as a prophylactic agent and definitely for those already using substances, including stimulants, alcohol, marijuana, and opiates.

Highlights from the ISBD meeting.

Roughly 15% of schizophrenia cases among young males may be preventable by avoiding cannabis use disorder (CUD). Not only does cannabis abuse markedly increase the risk of schizophrenia, its use has transgenerational effec...