Aaron S. Wolfgang, MD and Charles W. Hoge, MD reviewed data on cannabis in JAMA Psychiatry and found that there were big placebo effects and no evidence for effectiveness of cannabis in military personal. -- This negative ...

An article by researcher Jennifer M. Mitchell and colleagues published in the journal Nature in 2021 reported that MDMA was more effective than placebo at treating severe post-traumatic stress disorder in an 18-week phase ...

Theta burst stimulation. -- In a 2019 article in the journal Neuropsychopharmacology, Nicholas J. Petrosino and colleagues described findings from one year of follow-up with veterans suffering from post-traumatic stress di...

In a 2018 open study by C. Sophia Albott and colleagues in the Journal of Clinical Psychiatry, veterans with post-traumatic stress disorder (PTSD) and a simultaneous diagnosis of major depression were treated with six infu...

In a 2017 article in the journal Neuropsychopharmacology, researcher Michael S. Breen and colleagues analyzed five separate studies of post-traumatic stress disorder (PTSD) and found that sex and type of trauma affected th...

Post-traumatic stress disorder (PTSD) has been associated with decreased volume of gray matter in the cortex. Research by Linghui Meng and colleagues has revealed that the specific types of trauma that precede PTSD affect ...

A recent study clarified how cognitive behavioral therapy improves symptoms of depression and post-traumatic stress disorder (PTSD). The participants were 62 adult women. One group had depression, one had PTSD, and the thi...

Note: The following article discusses “off-label” treatments for the treatment of PTSD or traumatic brain injury, i.e. those which are not FDA-approved for these purposes. In some of these instances, there is no controlled...

Patients with PTSD often struggle with nightmares, but a treatment normally used for high blood pressure may also be able to prevent these sometimes horrific dreams. In a study that marks the third replication of this find...

At a recent scientific meeting, Thomas Neylan and colleagues reported that post-traumatic stress disorder (PTSD) may be connected to autoimmune illnesses. In this study, 673,277 veterans of the US military who had served i...

Sanne J.H. van Rooij reported in the Amer. J. Psychiatry (2026) that low frequency repeated transcranial magnetic stimulation (1 Hz rTMS) twice daily for 10 days over the right dorsolateral prefrontal cortex (in an area that connects with the right amygdala) had very positive effects in most aspects of PTSD compared to sham stimulation. They saw that: “Hyperarousal symptoms were also markedly lower in the active TMS group at 3-6 months post-therapy, compared with those in the placebo group." “We think that the full behavioral effects of active stimulation may take some time to emerge…. They suggested that targeted treatment with accelerated TMS like that delivered in the trial may, over time, change the brain in ways that render trauma-related memories less likely to result in hyperarousal, and more likely that trauma memories can be accepted and lived with, resulting in an ability of patients to “take their lives back.”‍