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THC

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Risk Factors
May 29, 2024

Adolescent Cannabis Use is Associated with Regional Decreases in Cortical Volume and Greater Decreases in Males than Females

Mona Darvishi of The Ohio State University reported that adolescent cannabis use is associated with regional decreases in cortical volume in 10 of 42 brain regions. -- In two of these regions, the superior frontal gyrus an...
Childhood
December 6, 2022

Adolescent Delta-9-tetrahydrocannabinol induces long-term neuronal disturbances in dorsal vs. ventral hippocampus

De Felice et al reported in Neuropsychopharmacology (2022) how adolescent THC exposure in a rodent model can induce significant morphological disturbances and glutamatergic signaling abnormalities in the hippocampus. The d...
Biology
April 21, 2020

In Animal Model, Long-Term THC Exposure Interferes with Cortical Control of the Nucleus Accumbens

Cannabis plant. Photo by Esteban Lopez on Unsplash -- In an article in the journal Biological Psychiatry, researchers Eun-Kyung Hwang and Carl R. Lupica reported that in rats, long-term use of THC (tetrahydrocannabinol) we...